Thoracic gas volume in early childhood.

Lung function from infancy to school age in cystic fibrosis.

The aim was to investigate pulmonary mechanics in patients with cystic fibrosis during infancy and again in early childhood to see whether infant tests predicted status at school age. Plethysmographic measurements of thoracic gas volume and airways resistance were made in 29 patients at 6 months and again at 5 years 10 months. Maximum flow at functional residual capacity was measured during inf...

Cognitive development in transposition of the great vessels.

Ten children who had had transposition of the great vessels (TGV) repaired, deep hypothermia, and cardiac arrest were examined. Seven children with acyanotic heart disease and 12 unaffected siblings were tested for comparison. Their intelligence, academic achievement, and behaviour was studied. The group with TGV had lower performance subscores on the intelligence test, an increase in somatic c...

Measurement of airway resistance and thoracic gas volume in infancy.

At what age do bronchodilator drugs work?

Using a modification of the forced oscillation technique we have measured respiratory resistance before and after nebulised salbutamol therapy in 32 wheezing children aged 7 months to 3 years 7 monts. 12 of the children were also studied in a total body plethysmograph. No child under 18 months of aged showed a greater than 5% fall in resistance or any fall in thoracic gas volume. In contrast, 1...

Lung function abnormalities at 6 months of age after neonatal intensive care.

Respiratory function was studied in 46 preterm infants (median gestational age 28 weeks) at 6 months of age. Respiratory function was assessed by measurement of thoracic gas volume, airways resistance (from which specific conductance was calculated), and functional residual capacity. To determine the effect of the duration of neonatal intermittent positive pressure ventilation (IPPV) on respira...